翻訳と辞書
Words near each other
・ EUJUST LEX
・ Eukanuba
・ Eukarpia (theonym)
・ Eukaryote
・ Eukaryotic Cell
・ Eukaryotic chromosome fine structure
・ Eukaryotic chromosome structure
・ Eukaryotic DNA replication
・ Eukaryotic elongation factors
・ Eukaryotic initiation factor
・ Eukaryotic initiation factor 4G
・ Eukaryotic large ribosomal subunit (60S)
・ Eukaryotic Linear Motif resource
・ Eukaryotic Pathogen Database Resources Centre
・ Eukaryotic Promoter Database
Eukaryotic release factors
・ Eukaryotic ribosome (80S)
・ Eukaryotic small ribosomal subunit (40S)
・ Eukaryotic transcription
・ Eukaryotic translation
・ Eukaryotic translation elongation factor 1 alpha 1
・ Eukaryotic translation initiation factor 4 gamma
・ Eukaryotic translation initiation factor 4E family
・ Eukelade
・ Eukey
・ Eukiefferiella
・ Eukrohniidae
・ EUL
・ Eul-Yong Ta
・ Eula


Dictionary Lists
翻訳と辞書 辞書検索 [ 開発暫定版 ]
スポンサード リンク

Eukaryotic release factors : ウィキペディア英語版
Eukaryotic release factors

Eukaryotic translation termination factor 1 (eRF1), also known asTB3-1, is a protein that in humans is encoded by the ''ETF1'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2107 )
In eukaryotes, this is the only release factor (eRF) which recognizes all three stop codons. The overall process of termination is similar in prokaryotes, but in the latter 3 separate release factors exist, RF1, RF2 and RF3.
== Function ==

Termination of protein biosynthesis and release of the nascent polypeptide chain are signaled by the presence of an in-frame stop codon at the aminoacyl site of the ribosome. The process of translation termination is universal and is mediated by protein release factors (RFs) and GTP. A class 1 RF recognizes the stop codon and promotes the hydrolysis of the ester bond linking the polypeptide chain with the peptidyl site tRNA, a reaction catalyzed at the peptidyl transferase center of the ribosome. Class 2 RFs, which are not codon specific and do not recognize codons, stimulate class 1 RF activity and confer GTP dependency upon the process. In prokaryotes, both class 1 RFs, RF1 and RF2, recognize UAA; however, UAG and UGA are decoded specifically by RF1 and RF2, respectively. In eukaryotes, eRF1, or ETF1, the functional counterpart of RF1 and RF2, functions as an omnipotent RF, decoding all 3 stop codons.〔〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Eukaryotic release factors」の詳細全文を読む



スポンサード リンク
翻訳と辞書 : 翻訳のためのインターネットリソース

Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.